Tag Archives: NRF

Mitochondrial Complex I activity signals antioxidant response through ERK5

Mitochondrial Complex I activity signal

The vast majority of eukaryotic cells perform oxidative phosphorylation (OXPHOS), which uses the energy released by the mitochondrial oxidation of certain metabolites, i.e. glucose, to produce adenosine triphosphate (ATP). OXPHOS is highly efficient in energy production but