Tag Archives: oxidative phosphorylation

Osteoarthritis alleviation by rewiring cellular energy metabolism

Osteoarthritis (OA) is a chronic disorder associated with degeneration of the joint, including articular cartilage, subchondral bone, synovial tissue, tendons, periarticular muscles that involves low-grade systemic inflammation. Recent studies have demonstrated the involvement of chondrocyte differentiation (hypertrophy)

Why are skeletal muscles not depleted of energy during intense exercise?

ATP is a universal carrier of energy in a form easily accessible for different reactions in the cell. Its hydrolysis to ADP and Pi (inorganic phosphate) drives processes that cannot occur spontaneously and require energy, for instance