Tag Archives: P-glycoprotein
Drugs from the sea: complex structures to fight a complex problem of resistance in cancer
It is well known that incidence of cancer cases figures among the leading causes of morbidity and mortality. Most of disseminated cancers share the common feature of not responding to anticancer drugs. This phenomenon is known as
Modalities to overcome cancer cells safeguard
The increase of intracellular concentration without raising the applied drug doses is big challenge for cancer treatments. Cancer cells employ multiple mechanisms to resists the anticancer drugs action. One of the mechanisms involves P-glycoprotein. The role of
