Tag Archives: retromer

Retromer in polarized protein transport

In living organisms, all cells contain different compartments called organelles. Each organelle, surrounded by lipid membranes, includes a characteristic set of resident molecules. Maintenance of such precise set of components in each organelle is critical for proper

Is VPS35 critical to prevent Parkinson’s disease?

Parkinson’s Disease (PD) is a severely debilitating motor disorder characterized by loss of dopaminergic neurons and increase of α-synuclein in a brain region known as the substantia nigra pars compacta (SNpc).  Although much progress has been made