Tag Archives: structural biology

Protein structure detection in intermediate-resolution cryo-EM maps using deep learning

AoS. Protein structure detection in intermediate-resolution cryo-EM maps using deep learning

Cryo-EM has established its position in structural biology as an indispensable method of choice for determining macromolecular structures due to recent technological breakthroughs. The recent years have observed a steep increase of biomolecular structures solved by cryo-EM,

Signaling in the brain studied – a role for receptor clustering?

Olfactomedin-1 is a signaling protein in the brain that plays various roles during early brain development. Brain cells (neurons) secrete the protein to the extracellular matrix, where it is known to be involved in several signaling pathways.

Human centromeric DNA is able to form quadruplex helices

The classical view of a chromosome that most of people have in mind is a cross-shaped figure, something like the letter X. Chromosomes look indeed like that when the cell is ready to divide and give rise