Daily Archives: January 9, 2016
Regucalcin controls prostate cell proliferation and glycolytic metabolism
Regucalcin (RGN) is a protein with multiple functions and facets, which seems to play an important role in tissue cell homeostasis by regulating the equilibrium between cell survival/proliferation and death, and also in the control of cell
Learning from evolution to target cancer with combinatorial strategies
Chemotherapy is the most prominently used therapy for many cancers yet it effects multiple and, in many cases, unknown targets. Of the most modern advancements in cancer treatment is the targeting of single key gene products, for
AntiVEGF therapy: hidden changes on heart and vessels
VEGF (Vascular endothelial growth factor) is a protein normally present in our organism that promotes the growth of new blood vessels, a process known as angiogenesis. Cancer cells produce this substance in large quantity, obtaining a continuous
Migraine, lifestyle, childhood
Migraine is one of the most frequently reported somatic complaints in childhood, with a negative impact on health-related quality of life. Headaches in childhood are subtended by primary headache syndromes with a significant negative impact on the
Headache is the third leading cause of disability in the world
Three years ago, the medical journal Lancet published the third Global Burden of Disease (GBD) study (GBD 2010). We wrote then of the political significance, and promise, of this report for people with headache. Migraine, an under-recognised,
What role do medications play in changes in sexual activity after a heart problem?
Heart disease affects millions of people worldwide. While advances in medical treatment have allowed many with heart disease to live longer, healthier lives, changes in quality of life often occur. This is particularly true for sexual activity,
Complementary therapies can increase survival in cancer patients
It is well known that a large percentage of cancer patients use some form of complementary and alternative medicine (CAM), usually with the goal of improving quality of life, providing supportive care as well as relieving pain
Metformin is a potential remedy for the treatment of Gaucher disease
Glycosphingolipids (GSLs) are amphipathic compounds consisting of oligosaccharides and hydrophobic chain of ceramide. They are ubiquitously distributed in the outer leaflet of the plasma membrane and believed to be involved in a large number of cellular processes,
Replacement of saturated with unsaturated fats had no impact on vascular function but beneficial effects on lipid biomarkers and blood pressure
Disease of the heart and blood vessels (referred to as cardiovascular disease (CVD)) is the primary cause of death worldwide. A key public health recommendation for reducing the risk of developing CVD is to lower our intake of
