Category Archives: Research

Finding therapeutic way to eradicate tuberculosis of the brain

Tuberculosis is one of oldest infectious disease in the world. It is caused by a bacterium called Mycobacterium tuberculosis, where it infects primarily the lung. Millions of individuals are infected with Mycobacterium tuberculosis. Even though we are

Ultrasound in medical education

Ultrasound is a type of energy that can be used in medicine for both making diagnoses and treating patients.   Like the sound of a voice, a person uses air passing across the vocal cords to produce noises

Treating prostate cancer with immunotherapy

Cancer immunotherapy induces the immune system to recognize and destroy cancer cells. These therapies can work through a number of ways but two of the most researched methods are therapeutic cancer vaccines and immune checkpoint inhibitors. Therapeutic

Escherichia coli K-12 as a model to understand gene regulation

Escherichia coli K-12, a bacterium of the normal flora of humans, represents one of the most important model organisms in biology. This microorganism has been completely sequenced at DNA level, and contains 4319 genes. An important element

Sweetness of recombinant human lysozyme

Here, we reported that lysozyme found in human milk elicits sweet taste as well as chicken lysozyme with 20-folds more sweetness than sucrose by weight. Lysozyme is an enzyme that degrades the bacterial cell wall and thereby

New method to isolate biofuel-producing bacteria

There has been much debate about converting foods like corn grain into fuel for our cars.  Even if all the corn grain in the US were converted to ethanol, it still wouldn’t make enough fuel to replace

Engineering social justice into self-driving vehicles?

Self-driving vehicles will soon be a central part of our transportation system. Their introduction promises several benefits, including improved traffic safety, mitigated fuel consumption, congestion, and pollution, and enhanced mobility for persons unable to drive. The introduction

Gold “bowtie” coming into reality on two-dimensional MoS2 surface

“Bowtie’’, which is a type of necktie, is very popular in our daily life. In some formal meetings or parties, bowtie is the normal choice to make you look good. Actually, this kind of bowtie structures of

Lipofuscin, lipofuscin-like pigments and autofluorescence

This paper provides a syntethic overview on lipofuscin and lipofuscin-like substances, with particlar reference to their biological significance as well as to their cellular origin and pathophysiological role. Special emphasis is also placed on the mutual relationships between

Filamentous bacteriophage organize bacterial biofilms into liquid crystals

At sites of chronic infection, bacteria form biofilms, clusters of bacteria encased within a slimy, polymer-rich coating called the matrix. Biofilms are of concern because bacteria within biofilms become tolerant not only to environmental stresses, but also

Should you be taking a statin drug?

Millions of patients are currently treated with cholesterol-lowering statin drugs that are prescribed to prolong life and prevent heart attacks. For patients who have never had a heart attack or stroke (primary prevention), statin therapy is typically

From cell to society: a nutritional intervention to offset the age-related loss in lean tissue mass

Society is aware of obesity. Defined by the WHO, obesity is an abnormal or excessive fat accumulation that may impair health. A 40y person with normal BMI will progress to obesity at 70y through an annual gain

What does the PROMISE trial mean for cardiac CT?

Current guidelines recommend functional testing (FT) such as exercise tests or nuclear tests (with very high radiation exposures) to identify those patients who have chest pain that may benefit from stents or bypass surgery.  Unfortunately, a vast

Case study of a successful metals recovery project

As we continue to invent, manufacture, and consume countless numbers and types of consumer goods, we need an increasing study supply of raw materials, especially metals. Although the earth’s metal resources are finite, we continue to mine

Changes in anti-predator behaviour of prey after large predator declines

Large carnivores are suffering severe declines worldwide due to their vulnerability to habitat loss, emerging diseases and persecution. Their loss has been attributed to changes in the abundance and behaviour of other species, including small mammals and

Compounds from Australian Eucalypts: the next wonder-drug for cancer?

If there is one tree that every Australian can relate to, then it would be the none other than the Eucalypt. No wonder they are considered as the only trees that have the power to unite the

Forecasting malaria using environmental and clinical predictors

In 1911, Christophers developed an early-warning system for malaria epidemics in Punjab based on rainfall, fever-related deaths and wheat prices. Since that initial system, researchers and practitioners have continued to search for determinants of spatial and temporal

Controlling gene expression in bacteria

Gene expression enables cells to implement the instructions encoded within the genes on their DNA. Being able to control gene expression is therefore key to this most fundamental biological process, so determining cell fate and behaviour. Cells

Analysis of volatile organic compounds

Entombed victims under the ruins of collapsed buildings, because of natural or man-made disasters, patiently wait for help in order to be identified, detected, safely extricated and finally saved by urban search rescue (USAR) teams. This is

A platform for measuring carbon and nitrogen levels of metabolism-related genes in durum wheat

Multiple lines of evidence confirm that as a result of human activities the greenhouse gas emissions are rising more rapidly than predicted and, consequently, the world is warming more quickly. Global climate change threatens for food security