Category Archives: Research

The SETOC: Visualizing carcinogenesis through a different lens

The Systemic-Evolutionary Theory of the Origin of Cancer (SETOC) is a recently proposed theory based on two fundamental principles: (i) Margulian evolution as a process of cooperation and endosymbiosis and (ii) Systemic cell biology understood as the

Cerebral venous hemodynamic in a rat model of acute epidural hematoma

AoS. Cerebral venous hemodynamic in a rat model of acute epidural hematoma

Traumatic brain injury (TBI) is currently one of the most serious public-health problems, with an annual global incidence rate of 319/100,000. TBI includes primary injuries directly caused by mechanical stress and shear forces, as well as secondary

Muscle pain treated with injected normal saline solution

AoS. Muscle Pain Treated with Injected Normal Saline Solution

Pain comes in all shapes and sizes. Ranging from acute to chronic, from nociceptive and myofascial to neuropathic, pain is a part of life. Myofascial or muscle pain, is among the most common. With a lifetime prevalence

A new procedure to accurately define Nitrate Vulnerable Zones

The Nitrates Directive of the European Union (91/676/EEC) aims to reduce and prevent water pollution caused by nitrates from agricultural sources. It establishes that water resources should be considered polluted when nitrate concentration exceeds 50 mg L-1.

Recording in the emergency department: illegal or immoral?

Patients and staff should expect privacy in emergency departments and should not be recorded without giving their consent in advance. Emergency departments (ED) use audiovisual recordings to document clinical information and to assist with diagnosis and treatment.

How PET ameliorates 90-Yttrium therapy in inoperable liver cancer patients?

Increased synthesis of blood vessels and blood supply are essential characteristics of a tumor to secure nutrient delivery and growth. One of the treatment options for inoperable liver cancer (hepatocellular carcinoma, HCC) is to apply a form of

A novel digital nasoalveolar molding approach for cleft lip and palate

AoS. A novel digital nasoalveolar molding approach for cleft lip and palate

Presurgical nasoalveolar molding (PNAM) is a widely accepted approach applied before cheiloplasty for infants with unilateral cleft lip and palate (UCLP), which can effectively reduce the width of the cleft gap, to align and approximate the intraoral

Effectiveness of infrared tympanic thermometry during physical activity in the heat at a solar radiation of 500 W/m2 or less

AoS. Effectiveness of infrared tympanic thermometry during physical activity in the heat at a solar radiation

Exposure to high solar radiation in the heat poses a thermoregulatory challenge and increased risks of exertional heat-related illness in workers and exercising individuals. Core temperature monitoring is important during physical activity in the heat to prevent

Arthroereisis for symptomatic flexible flatfoot deformity in young children

Flexible flatfoot is a common deformity in the pediatric population. The foot due to ligamentous laxity is unable to support the body weight at its three contact areas to the ground (The plantar aspect of the calcaneus,

Synergies between ultrasound and aminated nanoparticles in the synthesis of DHP pharmaceuticals

Today, attentions to the synergistic effects have raised due to bringing convenience and expedition into the complex processes. In the field of catalysis, synergistic effects between the ultrasound waves (USWs) and the nanosized heterogeneous species is one

Small waterbodies as indicators of elemental pollution in urban sediments

The impact of urbanization and industrialization on sediment quality of large rivers and lakes have been widely studied globally, however, small waterbodies, such as ponds and canals, are rarely studied collectively. Ponds and canals that form a

Fast and simple glyphosate detection using a functionalized surface

Glyphosate is the most widely used herbicide worldwide. It is used since the 1970s to dispose of weeds to increase yield. Since some years its use is under great debate because of its potentially cancerogenic effect and

Fast artificial intelligence for detecting the invisible

AoS. Fast Artificial Intelligence for Detecting the Invisible

Artificial Intelligence (AI) relies on synthetic neural networks, inspired by functional properties of living intelligent systems (brains) and learns autonomously on the basis of unsupervised learning procedures. Such learning permits, among other things, the analysis of changes

Social-economic factors predict state differences in opioid overdose rates

Media accounts of the opioid overdose epidemic emphasize the role of prescription drugs and, to a lesser extent, declining economic and social conditions. In support of the journalists’ accounts, opioid prescriptions, as measured in grams of morphine

T-cell subsets in HIV infection

AoS. T-Cell Subsets in HIV Infection

The human immunodeficiency virus (HIV) is a virus that assaults the body’s immunologic system. If HIV is not tackled, it can eventually drive the organism to AIDS, which a dreadful condition known as acquired immunodeficiency syndrome. In

Tracking mRNA in living cells using Pepper RNA aptamer

Messenger RNAs (mRNAs) are a class of biomolecules that are generated in the nucleus to carry genetic information from the nucleus to different parts of the cells for making functional proteins. Because of their importance, mRNAs’ trafficking

If you are cold, what two cold-sensitive ion channels TRPM8 and TRPA1 do?

AoS. If you are cold, what two cold-sensitive ion channels TRPM8 and TRPA1 do

Human and animals are capable of perceiving temperature stimuli due to the presence in the body of specialized sensory neurons in the peripheral and central nervous system. The sense of ambient and internal temperature is necessary to

Clinically utilized nalfurafine combined with naltrexone prevents excessive alcohol drinking and “relapse”

AoS. Clinically utilized nalfurafine combined with naltrexone prevents excessive alcohol drinking

Alcohol addiction poses massive public health costs [~15 million adult alcoholics with economic cost > $200 billion/year in the US]. Pharmacological studies in rodents have demonstrated that kappa-opioid receptor (KOR) agonists decrease alcohol drinking and reward. However,

Can [60]fullerene maintain good health and prolong lifespan?

AoS. Can [60]fullerene maintain good health and prolong lifespan?

Fatalists aside, who doesn’t want to live longer and in good health? But, obviously, to live longer it would be nonsense to put our health at risk. Yet, since we published a paper in 2012 on prolonging

Ti3C2-MXene based fluorescent biosensor for rapid detection of lung cancer biomarker

AoS. Ti3C2-MXene based fluorescent biosensor for rapid detection of lung cancer biomarker

Over the last decade, zero-dimensional (0D) and two-dimensional (2D) nanomaterials such as nanostructured metals, and graphene derivatives delivered an extraordinary impact as fluorescence quenchers or energy acceptors in developing fluorescent biosensors. However, these OD/2D materials have a