Category Archives: Research

Can we accurately diagnose different clinical variants of Progressive Supranuclear Palsy using IPMDS-PSP criteria?

AoS. Can we accurately diagnose different clinical variants of Progressive Supranuclear Palsy using IPMDS-PSP criteria

Progressive Supranuclear Palsy (PSP) is the second most common degenerative parkinsonian syndrome after idiopathic Parkinson’s disease. PSP is a clinically heterogeneous disorder with several clinical variants. The two most common clinical variants are the Richardson (PSP-RS) and

Microbial community assembly and the microbiome revolution

AoS. Microbial community assembly and the microbiome revolution

Microbial communities (i.e. groups of potentially interacting microbial populations that co-exist in space and time) most commonly represent complex and highly diverse assortments of microbial populations, each possessing different genomic features that reflect on their specific life

Exploring gap junction networks required for zebrafish skin pattern formation

The study of pattern formation has advanced to a new phase involving channel molecules acting on bioelectric signals, with gap junctions being major relevant factors. Gap junctions are composed of connexin proteins: six connexins form hemichannels/connexons on

Social rank recognition is altered in autism spectrum disorder

AoS. Social rank recognition is altered in autism spectrum disorder

Humans and many other animals spend their lives in social groups, along with constructing social hierarchy within the groups. Since social hierarchy is a principal determinant for allocation of limited resources for individuals in a group, assessments

Is that possible to prevent parasitic iatrogenic blood bank transmission?

AoS. Is that possible to prevent parasitic iatrogenic blood bank transmission?

Chagas disease (CD) is neglected tropical disease (NTD) that affects over 6 million people mainly in the poorest areas of Latin America. CD also represents a public health concern in non-endemic areas such as North America, Asia,

Waking a sleeping giant: How increasing Africa’s research output can benefit global cardiovascular health?

AoS. Waking a sleeping giant: How increasing Africa's research output can benefit global cardiovascular health?

Africa is home to 1.4 billion people, of whom 55 million suffer from cardiovascular disease (CVD). Despite this, Africa contributes to only 1.7% of the world’s cardiovascular science. We studied 179 clinical trials led by African researchers

Lipid nanoparticles loaded with CpG oligonucleotides exert an antitumor effect via immunomodulation

AoS. Lipid nanoparticles loaded with CpG oligonucleotides exert an antitumor effect via immunomodulation

Since the emergence of immune checkpoint inhibitors (ICIs), cancer immunotherapy has dramatically developed. However, its drawback is the low overall response rate to its therapeutic effect. The efficacy of immunotherapy is suggested to depend on the immune

Sustainable solutions: Tamarind Seed Kernel powder (TKP) adhesive as a green alternative for lignocellulosic composites

The majority of petroleum-based adhesives applied in the wood industry today, particularly formaldehyde-based adhesives. Their application trend is increasing due to their wide availability, superior bonding, durability, and resistance to heat and moisture. However, formaldehyde-based adhesives continuously

Fatigue assessment strategy using Bayesian techniques

AoS. Fatigue assessment strategy using Bayesian techniques

The fulfilment of the probabilistic fatigue characterization of materials based on the S-N field requires the definition of the statistical distribution of the percentile curves of the failure probability, interpreted as a simplification, by their confidence bands.

Starch fatty acid esters – versatile bio-based thermoplastics

The biopolymer starch is well-known in the kitchen for baking, cooking, and as a component of flour and is available in large quantities. This makes starch interesting as sustainable resource to convert it into biodegradable products to

From complexity to simplicity via microbial division of labor inspired by Nature

AoS. From complexity to simplicity via microbial division of labor inspired by Nature

If someone were to put Nature under a microscope, it would become obvious that microbes are present in all environments on our planet. Microbes are often forced to interact within proximity and share resources as an important

Am I at risk of developing diabetes if exposed to insecticide?

AoS. Am I at risk of developing diabetes if exposed to insecticide?

The answer is: it depends. Of course, there is no trivial answer to an open question like that when referring to scientific investigation. But we can make you think better before exposure to certain pesticides like malathion.

Murburn concept explains why oxygen is acutely needed to sustain life

Murburn concept (from “mured burning”, signifying a restricted uncontrolled oxidative process) provides a tangible rationale why oxygen is so quintessential for immediate maintenance of life-order. It postulates that oxygen-centered diffusible reactive species (DRS, like superoxide radical) are

Mortality risk among cocaine users after and before economic recession

AoS. Mortality Risk Among Cocaine Users after and before economic recession

This study targeted residents in northern Italy who turned to a public treatment centre for primary cocaine use between 1982 and 2016. Its aims were to estimate mortality risk, and to examine mortality for subjects who have

Molecular classification of glioma stem cells

Comprehensive genetic analysis of glioblastomas by The Cancer Genome Atlas (TCGA) has proposed a new classification based on genetic abnormalities. The characteristic genetic abnormalities identified in the TCGA are promising candidates for novel molecularly targeted therapies, and

BioID screen for bacterial virulence proteins: new tools for infectious disease research

AoS. BioID screen for bacterial virulence proteins

The discovery of penicillin in the 1920s revolutionized our ability to treat bacterial infection. However despite the introduction of antibiotics, infectious bacterial pathogens remain an immense challenge for the healthcare community. The incidence of infection by antibiotic-resistant

Layer-dependent fast electron transfer at the Zn-phthalocyanine-few-layer graphene interface: theory explains

AoS. Layer-Dependent Fast Electron Transfer at the Zn-phthalocyanine-few-layer graphene Interface

The photo-induced effective interfacial charge separation in Zn phthalocyanine/few-layer graphene heterojunctions has been a promising observation for fabrication of efficient energy-conversion devices. Few-layer graphene are two-dimensional (2D) systems composed of one-atom-thick honeycomb layers of sp2 -hybridized carbon

Emerald Ash Borer attacks trees revealing early chemical clues

AoS. Emerald Ash Borer attacks trees revealing early chemical clues

The Emerald Ash Borer (EAB), Agrilus planipennis, is a major global forest pest (a buprestid beetle) that has decimated ash trees (Fraxinus species) throughout Europe and Asia. Since this nonnative invasive insect was introduced into the U.S.

Your pharmacist will see you now!

Atlas of Science. Your Pharmacist Will See You Now

Public perception of pharmacists might be limited to dispensing medications. However, pharmacists are trained to deliver patient care to help patients improve their health-related outcomes and achieve their goals. Recognizing the expertise of pharmacists, the State of

A mixture of plant extracts attenuates postprandial glycemia

AoS. A mixture of plant extracts attenuates postprandial glycemia

The epidemiological studies demonstrate beneficial effects of a regular consumption of fruits, vegetables or grains on human health, which is usually a result of their lower caloric value and dietary fiber and specific bioactive compounds present in