Category Archives: Research
How can we measure problematic videogame use among adolescents?
Playing video games is currently one of the most frequent leisure activities in young people and adolescents, but it generates a social alarm because it is associated with negative consequences such as family or scholar problems, reduction
Strengthening the Paris Agreement by supply-side climate policies
To reach the Paris Agreement’s goal of keeping global warming well below 2 degrees, much of the world’s deposits of oil, gas and coal must be left permanently in the ground. In an article published in Science
Why photobiomodulation therapy is helpful for diabetic wound healing? Fibroblast answers!
It is an obvious well-known issue that diabetic wounds are poorly healing, but the molecular and cellular alterations leading to this impairment is not clear. Many studies concluded the dysfunction of dermal fibroblasts as the main responsible
Modulating the distribution and fate of MSCs following therapeutic delivery may enhance their efficacy
Mesenchymal stem/stromal cells (MSCs) can be isolated from multiple adult tissues and have been shown to produce factors which can protect cells from diverse injurious stimuli, favourably modulate the immune response, and enhance tissue reparative and regenerative
The roles of mesenchymal stem cells secretome in diabetic wound healing
There has been a fourfold rise in the number of diabetics from 108 million in 1980 to 422 million in 2014 and by 2040 the number will reach to 642 million. Diabetes mellitus drastically influences normal functioning
Upstream open reading frames (uORFs) as translational regulators in human disease
The messenger RNA (mRNA) translation process is a key step of gene expression, whose regulation allows the cell to rapidly change protein synthesis in a spatio-temporal manner in response to different stimuli. Translation comprises four steps –
Medical grade honey facilitates the healing of minor injuries in pediatrics
Children are at risk to injuries and wounds as it is their nature to play and explore in adventurous environments. At the same time, they are less experienced in calculating the risk when performing some stunts. However,
Electronic liquid crystal: A key ingredient for solving a long-standing mystery of the high-temperature superconductivity
The phases of matter are characterized by the symmetries inherent to each state. Imagine the freezing from water to ice. This phase transition is accompanied by the crystallization of H2O molecules, forming a periodic structure in a lattice.
Investigating SOCS3 as a new target for drugs to treat pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) is a fatal disease caused by the walls of the small blood vessels that supply the lungs walls becoming thicker (Fig. 1) and unable to adapt to changes in blood flow, resulting in
The quest for smart radio frequency materials
Reconfigurable and tuneable wireless devices are the ultimate goal of all generations of wireless technologies – starting from the first generation all the way to the current, fifth generation. And the interest is ever growing. It is
Extracellular cytochrome c: a novel damage-associated molecular pattern (DAMP) of the brain
Cytochrome c (CytC) is a protein that is normally located inside mitochondria where it participates in the energy-generating processes of cells. Since mitochondria are essential for life, these CytC-containing organelles are found in most animal cells. The
Interesting structural properties of auricin and its biosynthetic gene cluster
Streptomycetes belong to the main producers of secondary metabolites with a broad range of biological activities. A large number of these products belong to polyketides. These structurally diverse compounds are synthesized by a repeated decarboxylative condensation from
Photonic biosensors for mycotoxin detection in milk
Contamination of food and agricultural products by various types of toxigenic molds (fungi) is a serious and global problem. Fungal toxins, in particular, mycotoxins produced by several species of fungi are naturally present in food species such
Prostate volume estimation: is there need for a change in the standard method?
As men age, prostate enlargement often leads to complications such as obstruction of the bladder neck and urinary retention with potential consequences on the kidney. Therefore, knowledge of prostate volume is required to help clinicians effectively manage
Anatomic variation of the nasopalatine canal among dentate, partially edentulous and completely edentulous subjects
The rehabilitation of the upper central incisors with the use of implants is one of the most complex aesthetic challenges. The anterior sector has important anatomical implications: resorption of the alveolar bone and the nasopalatine duct (NPD),
Chemoselective Intramolecular carbene C-H insertions of 2-diazo-2-sulfamoylacetamides
The transition-metal-catalyzed intramolecularly aliphatic and aromatic C-H insertions of diazo amides provide useful and important transformations to efficiently synthesize nitrogen-containing heterocycles with the new generated C-C bond. The reactivity of different diazoamide derivatives has been well studied
Non-local deformation sensing in nanoscale
Nanoindentation and pico-indentation based on atomic force microscopy (AFM) are commonly used for the evaluation of material mechanical properties using the depth-loading profile measured at a specific location of the material. However, the interpretation of the measurement
Sustainable ZnSnO3 nanowires produced by a low-cost solution process
Oxide materials, and more specifically, multicomponent oxide materials, have been widely explored in thin-film technology, being the indium-based materials very common. For example, conductive indium-tin oxide (ITO) or semiconductive indium-gallium-zinc oxide (IGZO) are key-materials in billion-dollar industries
Particularly harmful particles? Sifting out the dirt to find the microplastic effect
Research on microplastic effects in aquatic environments has expanded dramatically in the last decade. However, many important questions remain largely unanswered. We still do not know, for example, what are the safe levels of microplastic in different
The anterolateral ligament of the knee – an anatomical phantom
In 1879, Paul Segond published an article on clinically present and experimentally created bloody effusions in sprained knee joints. As an associated aggravation, he reported the formation of comminuted fractures of the lateral tibial condyle caused by
