Category Archives: Research

Authentication of Egyptian blossom honeys

Floral discrimination of clover and citrus honeys from Egypt against ‘’unknown’’ honeys from Greece based on 11 easily assessable physicochemical parameters and discriminant analysis

Twenty-two blossom honey samples (clover and citrus honeys) were collected from the greater Cairo area during harvesting year 2014-2015. The main purpose of the present study was to characterize the aforementioned honey types and to investigate whether

Functional significance of interhelical interactions between aspartic acid and cysteine residues in microbial rhodopsin

proton-pump type microbial rhodopsins

Microbial rhodopsins are photoreceptive seven-transmembrane proteins that contain all-trans retinal as a chromophore. Upon photon absorption, these proteins undergo a cycling photoreaction, where first the initial trans-to-cis isomerization of retinal induced by illumination leads to the formation

Treatment of experimental eye inflammation with a single subconjunctival injection of liposomal steroid

Treatment of experimental eye inflammation

Non-infectious anterior uveitis is an inflammatory condition in the front of the eye that can potentially lead to blindness. The current gold standard for treatment is with steroid eyedrops.  However, this treatment has several disadvantages. Very little

Simplified molecular diagnostics on a chip for point-of-care diagnostics

Simplified Molecular Diagnostics on a Chip for Point-of-Care Diagnostics

Analysis of blood, urine, and saliva often serves as the primary basis of diagnosis and treatment. Clinical specimens contain signature molecules (‘markers’) such as proteins and nucleic acids that are indicators of infection, cancer, and other diseases,

Do patients return to sport activities after total hip replacement?

Pooled data for number of patients participating in any sport pre- and postoperatively

Total hip replacement (THR) is a successful procedure to treat end-stage hip osteoarthritis. The procedure is increasingly performed in adults of working age, who often wish to return to highly demanding activities, including a return to sports

Reactive oxygen species, Devil or Angel?

Reactive oxygen species

Reactive oxygen species (ROS) have an amazing oxidative potential with oxidative stress and could abolish the integrity of living cells. Vigorous production of ROS can damage mitochondria and DNA, which would persistently destroy the cells and might

How cancer cells communicate with nervous and immune systems

In the last decade, studies have shown that cancer cells can influence their environment and bi-directionally communicate with other systems including immune and nervous systems. The neuro-immune interaction is a key player in influencing cancer development and

Using a uniform definition for growth restricted fetuses

sentation of the possible overlap between FGR and SGA and between AGA and LGA

Once a woman gets pregnant, the fetus develops and grows through exchange of oxygen and nutrients between the mother and fetus in the placenta. Each fetus has its own growth potential. Therefore, some fetuses are smaller than

Can “low calorie”-oil enhance the secretion of incretin hormones with beneficial effects on diabetic patients?

Time courses for plasma GLP-1 following ingestion of olive oil and carrot (squares), C4-dietary oil and carrot (circles) and carrot alone (crosses).

When the human body digests dietary fat (triacylglycerol), hormones from the intestine called incretins are released from the small intestine. These hormones stimulate insulin release and inhibit food intake. The mechanism for the fat-induced incretin release involves

Nanotechnology, is it something useful for future agriculture?

Nanotechnology has been applied in various fields – biomedicine, electronic devices, renewable energy   optical electronic medicine, physics, pharmaceutics. Does it have a place in agriculture? It is generally accepted that manipulation of a crop’s native microbiome represents

Can the heart get cancer? Quite rare, but yes

Can the heart get cancer

To many, the heart seems as an unusual location for cancer. In fact, most tumors that affect the heart are metastatic in origin (start in other organs and disseminate to the heart). Primary cardiac tumors (tumors that

Hearing the light: Improved frequency resolution of optical vs. electrical inner ear stimulation

Auditory signals, including human speech, are characterized by many features, one important being sound frequency, which is perceived as pitch. In normal hearing people, the cochlea in the inner ear translates different sound frequencies into neural activation

How well can serum miRNAs diagnose amyotrophic lateral sclerosis patients?

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that damages motor neurons. As the disease progresses, patients gradually loose exercise capacity. Finally, they die due to the lack of breathability. No effective therapy was found for ALS

Effect of exposure-age on chromosomal rearrangements in methyl isocyanate (MIC) gas exposed survivors

Exposure age and chromosome aberrations

Methyl isocyanate (MIC) gas disaster appeared one of the world’s worst industrial disasters by claiming a huge toll of human lives instantly and as its aftermath effect. Besides respiratory, ophthalmic and psychological disorders, stress leukogram, including anemia,

LMO1 regulates a novel oncogenic pathway druggable for neuroblastoma

LMO1 regulates a novel oncogenic pathway druggable for neuroblastoma

Neuroblastoma (NB) is derived from neural crest cells and its main developing sites are adrenal gland and sympathetic ganglions. It is the most common extracranial solid tumor in childhood, accounting for more than 7% of malignancies in

Concerns over dosing oral anticoagulants in clinical practice

over dosing oral anticoagulants in clinical practice

Atrial fibrillation (AF) is a heart condition characterized by an abnormal rhythm leading to irregular beat. An important consequence of AF is an incomplete emptying of the atria (upper heart chamber) leading to blood stasis and, potentially,

IL-2/IL-3 interplay mediates growth of CD25(+) acute myeloid leukemia cells

acute myeloid leukemia cells

A variety of cytokines regulate the survival, growth, differentiation and apoptosis of leukemia cells. Accordingly, aberrant or excessive expression of their receptors may be associated with the biological activity of leukemia cells, and hence with the outcome

Detecting math ability with brain potentials

Detecting math ability with brain potentials

It is known that the various individuals differ in their ability to perform arithmetic calculations. Some people can find mathematics an extremely easy exercise while for others it can become an insurmountable problem. For example, a significant

Our biological clock controls mitochondrial activity in a tissue-dependent manner

The molecular circadian clock and tissue-specific clocks

Mitochondria are the cell organelles that are responsible for the largest part of cellular energy production. Within these organelles both the tricarboxylic acid cycle (TCA cycle) and oxidative phosphorylation (OXPHOS) are taking place. In these cycles ATP,

Coastal wetland plant responses to elevated carbon dioxide

saltmarsh, coastal wetlands, nitrogen uptake, carbon dioxide

Coastal wetlands are some of the most efficient habitats globally when it comes to assimilating carbon dioxide from the atmosphere and storing it in soil. This is mainly due to the fact that many coastal wetland plant