Tag Archives: ageing

Can [60]fullerene maintain good health and prolong lifespan?

AoS. Can [60]fullerene maintain good health and prolong lifespan?

Fatalists aside, who doesn’t want to live longer and in good health? But, obviously, to live longer it would be nonsense to put our health at risk. Yet, since we published a paper in 2012 on prolonging

Lipids keeps shrinking with aging and neurodegeneration

AoS. Lipids keeps shrinking with aging and neurodegeneration.

I remember when my Biology teacher at the secondary school introduced us for the first time to the biochemical components of the living cells. I was immediately fascinated by the elegant code making of the nucleic acids,

Mitophagy in health and disease

Mitophagy in health and disease. AoS

Mitochondria are cellular organelles specialized for energy production, and critically influence several features of cellular metabolism and physiology. Maintenance of a healthy mitochondrial pool is a prerequisite for cellular and tissue homeostasis. Compromised mitochondrial function results in

Horny skin layer enhances the skin barrier function and water bonding with increasing age

Human skin consist of three layers – epidermis, dermis and subcutaneous tissue. The main age–related changes in the skin are well investigated for the dermis and include the delay of bio fluids’ microcirculation, reduced synthesis of extracellular

Acting in mechanisms of aging to delay/prevent Alzheimer’s disease

Alzheimer’s disease (AD), a severely debilitating and ultimately fatal brain disorder, affects millions worldwide. To date, clinical efforts to find a cure or adequate treatment have met with dispiriting failure. The disease is now on an ominous

Effect of alpha-fetoprotein on lifespan of old mice

Alpha-fetoprotein (AFP) is one of the best-known embryo-specific proteins. It is primarily known as an oncomarker for tumors of the liver and gastrointestinal tract, but its antitumor effects have also been shown. AFP is the prevention of

Natural aging as a sequential poly-systemic syndrome

A generalized approach to aging is possible based on the General System theory of aging, predicated on the General Model of aging. The fundamental cause of aging is the law of entropy increment in incompletely open systems.

Molecular mechanism of phenotypic plasticity

Darwinian evolution is considered to be the way that life adapts in every possible environment in Earth. The great evolutionary biologist of the past century Theodosius Dobzansky used to say: “Nothing in Biology Makes Sense Except in

Mild cognitive impairment in older people around the world

The global population is ageing rapidly, and bringing with it an increase in the number of people experiencing physical and mental health conditions associated with older age. Mild cognitive impairment (MCI) is a common condition among older

MicroRNAs fighting muscle wasting during ageing

Have you ever wondered why we age? With time, our joints, bones and muscles become weaker; wrinkles appear and we lose hair and sense of hearing and sight. However, not only our body experiences external changes; inside,

Why do some people cope well but others don’t? Resilience and vision impairment in older people

Some people fare better than others when faced with adversity; they appear to be more ‘resilient’. There are around two million people with a vision impairment in the UK, the majority of whom are aged over 60.

From cell to society: a nutritional intervention to offset the age-related loss in lean tissue mass

Society is aware of obesity. Defined by the WHO, obesity is an abnormal or excessive fat accumulation that may impair health. A 40y person with normal BMI will progress to obesity at 70y through an annual gain