Tag Archives: ATPase

Na/K pump mutations lead to hypertension by impairing Na+ and K+ transport

Aldosterone is a hormone that regulates blood pressure by increasing the amount of salt and water that your body retains as blood is filtered through the kidney. Aldosterone is produced by specific cells in the adrenal gland

Calcium ion by replacing magnesium ion unravels an unexpected role for the mitochondrial F1FO-ATPase

The F1FO-ATPase/synthase is universally known as a complex enzyme machinery which, embedded by the FO portion in the inner mitochondrial membrane and the catalytic F1 sector protruding in the matrix, matches the transmembrane proton flux which occurs

How the mitochondrial F1FO-ATPase can be chemically switched on/off and serve as drug target

The mitochondrial F1FO-ATPase is well known to play the main role in synthesizing most of ATP, thus providing energy to living cells under aerobic conditions. However the enzyme complex can also  work in reverse and split ATP

Astrocytic modulation of brain waves

The human brain contains two major cell populations: neurons and glia. While neurons can propagate electrical signals, known as action potentials, glial cells remain electrically unexcitable. For this reason, for many years, they were thought to merely