Tag Archives: cell physiology

Unregulated oxygen levels in mammalian cell culture changes cell physiology

As aerobic organisms we continuously utilize oxygen from the surrounding environment which ultimately participates in the formation of useful bioenergetic intermediates. Approximately 21% of the air we breathe is composed of oxygen, but the quantity of oxygen

HspB1, a polypeptide sensor whose structure reacts to changes in the physiology and environment of the cell

The small heat shock protein HspB1 acts as an ATP-independent chaperone helping cells to cope with stress-induced aberrantly folded polypeptides. Other interesting properties of HspB1 are its constitutive expression in many unstressed human cells and its up