Tag Archives: GABA

Parkinson disease: a tale of three neurotransmitters

The progressive loss of dopaminergic innervation of the basal ganglia, in particular of the dorsal striatum (putamen) is responsible for the motor signs of Parkinson disease such as bradykinesia, rigidity and loss of postural reflexes. Present therapies

Delay of GABA switch due to early – life stress leads to developmental disorder

Early-life stress, such as child neglect and abuse, is referred as one of the most prominent risk factor causing lasting social problems, which influence later development of psychopathologies. One specific sensitive period in neural development occurs during