Tag Archives: intracellular protons

Verapamil and a loop diuretic modestly reduce the intracellular pH of cortical neurons: a contribution to their anti-seizure potency?

A tight regulation of the intracellular pH ( pHi ) is needed to preserve essential cell functions, e. g. involved in cell communication and viability ( Fig. 1A ). In mammalian cortical neurons, pHi – regulation is