Tag Archives: microtubules

How a cellular samurai may be linked to autism

Inside cells, a highly dynamic and ever-changing cytoskeleton network determines cell shape (permanent or temporary), powers movement (intracellularly or on a substrate), aids cell division and segregation of chromosomes in daughter cells, and supports cellular extensions like

Microtubules slide neurons home

Brain development requires neurons, the most sophisticated information-carrying cells in the body, to migrate from where they are born to faraway destinations where they finally settle down and take up residence.  During its journey, a young neuron

How cancer cells resist the action of microtubule-targeting chemotherapeutic drugs? A study of β-tubulin mutations

Microtubules (MTs) are essential structural components of cells. They are made up of polymers of protein subunits of α,β-tubulin and are highly dynamic, undergoing rapid phases of assembly and disassembly. The dynamic behavior of MTs is essential

Oligodendrocyte Tau’s failed quest for microtubules results in myelin decrease and falling

Oligodendrocytes make a good-sized myelin that surrounds axons and allows humans to walk and see. In contrast, when axons do not get enough myelin, axonal function is incapacitated, with resulting deficits in cognition, behavior, and in the

An intracellular membrane system helps cells to divide

Cell duplication is the fundamental requirement for the development of multi-cellular organisms, a process that relies on two basic events: replication of the genetic information and the consequent separation of this information into two daughter cells. The