Tag Archives: NMJ

The Neuromuscular Junction: a core interpreter in the nerve-muscle dialog

AoS. The Neuromuscular Junction

Muscle and nerve communicate at the level of a specialized region, namely the neuromuscular junction (NMJ), a synaptic connection where the peripheral nervous system contacts skeletal muscle fibers, governing crucial vital processes, such as body voluntary movements

Motor nerve terminals with fast downregulation of Syt1 are more vulnerable in Spinal Muscular Atrophy

Spinal Muscular Atrophy (SMA) is the most frequent genetic cause of infant mortality. It is caused by mutations or loss of the SMN1 gene, which codifies for the Survival of Motor Neuron (SMN) protein. SMN has an