Tag Archives: nucleic acids
Specific synthetic nucleic acids instead antibodies
For a long time immunological methods have been applied in biological research as well as for detection and evaluation of various substances in clinical analysis of body fluids. Serum proteins, antibodies, form integral parts in all variants
Progress in macromolecular crystallography
The importance of crystallography was recently highlighted by the declaration by UNESCO of the Year of Crystallography 2014. This presented a good occasion to recall the advances of macromolecular crystallography achieved since its birth, more than half
Helicase and ribosome share a common mechanism of nucleic acid unwinding
In the cell DNA is present in the duplex form and many messenger RNAs (mRNAs) can form duplex structures. To access the genetic information (represented by nucleotides or codons) on the single-stranded (ss) nucleic acids (NA) by
Human centromeric DNA is able to form quadruplex helices
The classical view of a chromosome that most of people have in mind is a cross-shaped figure, something like the letter X. Chromosomes look indeed like that when the cell is ready to divide and give rise
