Tag Archives: oligomerization

Receptors talking: solo vs chorus

Receptors talking: solo vs chorus. Atlas of Science

Multi-cell organisms, including humans, need reliable and timely communication between cells to function. Every cell is surrounded by the plasma membrane made of lipids, which separates it from the environment. Receptors localized on that membrane are proteins

HspB1, a polypeptide sensor whose structure reacts to changes in the physiology and environment of the cell

The small heat shock protein HspB1 acts as an ATP-independent chaperone helping cells to cope with stress-induced aberrantly folded polypeptides. Other interesting properties of HspB1 are its constitutive expression in many unstressed human cells and its up