Tag Archives: rapamycin

Metformin and AMPK link cancer stem cell elimination with the potential eradication of HIV

Cancer stem cells (CSCs) are cancer cells that exhibit several stem cell-like qualities that are characteristic of embryonic or adult stem cells, including self-renewal, differentiation, and the ability to initiate tumorigenesis. CSCs, similar to adult stem cells

A new chance for rapamycin

Rapamycin is a bacterially-produced drug first discovered in the soil of Easter Island, and currently used as an immunosuppressant for organ transplantation and the treatment of certain types of cancer. Rapamycin has received popular attention following the

Putting mammalian target of rapamycin on track

Mammalian target of rapamycin (mTOR) is the target protein of rapamycin, a bacterial metabolite in Streptomyces hygroscopicus primarily found in the soil sample from Easter Island in South America thirty years ago. Since mTOR was discovered in