Tag Archives: systems biology

How did computers help us to find biomarkers for corticosteroid resistance in asthma through systems biology approach?

Asthma is a chronic disease that affects the lower airways, hampering the air movement in the lungs and the gas exchange. Asthma is characterized by bronchial inflammation that, particularly during an asthma attack, results in difficulty of

Computational systems biology in cancer brain metastasis

Cancer metastasis, especially cancer brain metastasis, is a complicated process representing the major cause for cancer-related deaths worldwide. A better understanding of the underlying mechanisms of such malignancies will enable us to develop more efficient therapeutic strategies.

Secret of cardiovascular diseases (CVDs) hidden in small molecules

Diagnosis and treatment of cardiovascular diseases (CVDs) are a great challenge for today’s medicine. It also results from not fully explained pathomechanisms underlying their development and progression. The group of CVDs is a very complex mixture of

Dissecting how cells communicate to prevent cancer relapse

Protein kinases are a class of enzymes that are responsible for the transfer of phosphates onto other proteins. These phosphate groups, although small, can change the behaviour of the protein itself, or the behaviour of those it