Tag Archives: tumor suppressor

Targeting microRNAs for thyroid cancer therapy

Schematic model explaining the oncogenic actions of miR-146b and the consequences of its inhibition in thyroid cancer

The thyroid gland is a small butterfly-shaped endocrine organ located at the base of the throat, just below the Adam´s apple. Its function is to concentrate dietary iodine from the bloodstream and produce thyroid hormones, which have

Is the best cancer offense a good defense?

Although the unique DiRas (Distinct subgroup of the Ras family) family of small GTPases shares homology with the pro-oncogenic Ras GTPases, it has tumor-suppressive actions. DiRas1 (also known as Di-Ras1 or Rig) has been reported to be