Yearly Archives: 2015
The development of a new blood substitute
The first transfusion ever performed is generally attributed to James Blundell in the beginning of the eighteenth century. Since Blundell’s experiments until the beginning of the twentieth century, transfusion was considered an extremely risked procedure with general
What Saudi women don’t know is killing them
Dozens of types of human papillomaviruses (HPVs) have been identified. While low-risk HPVs cause skin and genital warts, high-risk HPVs can lead to cancers of the cervix, vulva, vagina, penis, oropharynx, and anus. Recent studies have reprted
Phospholipase A2 group IVc blocks mammary tumor apoptosis
The Hirosaki hairless rat (HHR) is a mutant rat strain with autosomal recessive inheritance spontaneously derived from the Sprague-Dawley rat (SDR). The hairless phenotype of HHRs is due to the deletion of basic hair keratin genes, and
Sugars in circulating blood reflect breast cancer biology
In our studies, consisting of measurements and analyses, we have shown that the sugar composition in the serum of breast cancer patients reflects the biology of their breast tumours. Patients with different kinds of breast tumours have
Indoor air quality is strong affected by ambient air
Air pollution is now a major concert of public of China as well as many developing country. Monitoring data show severe ambient air pollution in many large cities. Since most people spend a large fraction of time
Technology to seek the elixir of hunger and satiation
Nowadays eating too much food or not enough are major social problems. Can we find identify medicine to promote either behaviour? Serendipity still drives first-in-class medicine identification. Hence, increasing the number of drugs tested increases the odds
Differentiation of pathogenic races of the lentil anthracnose pathogen C.lentis using effectors
The genus Colletotrichum has been under revision for the last decade. It contains species of high economic importance as pathogens of major crops, but also includes species that are model organisms to study host-pathogen interactions. The hemibiotroph
Effect of resveratrol on chemotherapy of a fatal childhood cancer
The natural polyphenolic compound resveratrol, found in red wine, dark chocolate, and peanuts, may confer health benefits in humans. It is a powerful antioxidant that has been suggested to alleviate age-related pathologies, such as type II diabetes,
Mother sharks transfer radioactive contaminants to their young
When nuclear accidents like that at the Fukushima Dai-ichi Nuclear Power Plant release man-made radionuclides into coastal marine waters the resident biota are exposed by way of several environmental pathways. The commonly studied pathways for fishes are
Determination of breath alcohol value after using mouthwashes containing ethanol
Mouthwashes are devices frequently used and suggested by dentist. Some mouthwashes contain ethanol (MCE), in order to improve their antibacterial activity. In Italian legislation there are a series of judgments reporting cases of drivers who resulted positive
Canine demodicosis – how to solve a problem ASAP?
Demodex mites cause disease in the skin of immune debilitated dogs. Demodex are species-specific, follicular mites that are found as a normal resident on most species of animals and in humans. Demodicosis is rare in the horse,
Simple method for measuring important components of cannabis in blood
The first recorded use of cannabis sativa, commonly called hemp, was by the ancient Chinese as early as 4000 BC. It was used as a fiber source for textiles, ropes, and paper. In addition, medical and entertainment
Highlighting inflammatory markers in anxiety disorders
Anxiety disorders, often originating early in life, are very common and effect 28.3% of the population. With this high prevalence comes an associated cost to the economy, mostly related to the extensive overuse of primary care services
Using cheminformatics to aid in the discovery of new drugs
Finding new medicines is a difficult and expensive endeavor and grows more difficult and expensive with every passing year. Thus, new ways to streamline the process are desperately needed by the pharmaceutical industry. Once upon a time,
Mutations in the gene DLL4 cause Adams-Oliver syndrome
Adams-Oliver syndrome (AOS) is a rare hereditary disorder that occurs in 1 in 225.000 individuals and is characterized by the presence of both scalp and limb defects. Congenital anomalies of the heart and blood vessels are also
Kidney disease dramatically affects whether patients should undergo vascular interventions
Kidney disease is a significant risk factor for poor outcomes following vascular surgery, and should be taken into consideration when evaluating patients for elective vascular interventions. Patients with kidney dysfunction who are recommended intervention by a vascular
Gelatin composites for controlled release of actives
During the 1950s the pharmaceutical market was flooded with oral products promising a prolonged release of actives. Since then a constantly growing effort has been devoted to the design of materials and formulations able to spatially and
Regular physical activity protects against depression after myocardial infarction
Depression is common and estimates suggest that in a family of four, one of the family members will likely suffer from mental health problems. Depression is even 3 times more common in patients after a heart attack
A method for studying mouse mammary tumorigenesis
Metastasis is the last step of primary breast cancer progression in which cells from the primary tumor leave and go to other organs. Breast cancer cells often metastasize to the lung, among other organs. Each step in
Psychological distress during and after the armed conflict in Burundi
Armed conflicts can have important and long lasting effects on the physical and mental health of people exposed to the. Especially in low and middle-income countries where not only the majority of conflicts take place but also
