Yearly Archives: 2017

The flipside of cystic fibrosis protein transport

Deficiency of ATP8B1 in humans causes severe progressive liver disease that is characterized by impaired bile flow. Besides liver disease, many ATP8B1 disease patients develop extrahepatic symptoms of yet unknown etiology such as pulmonary infection and defects

Why narcoleptic mice exhibit faster recovery from sickness behavior?

Hypocretin/ataxin-3 mice (which are postnatally depleted of hypothalamic hypocretin neurons) were administered LPS. As a result, hypocretin/ataxin-3 mice were increased in sleep compared with wild-type littermates and showed faster recovery from sickness behaviour. We examined changes in