Daily Archives: May 25, 2020

Inhibition of bovine insulin amyloid fibrillation and toxicity by silibinin

The misfolding and subsequent aggregation into β-sheet rich assemblies of endogenous polypeptides, such as β-amyloid peptide, tau protein, α-synuclein, and insulin are the underlying causes of diabetes and many neurodegenerative diseases. Although, no sequence or structural similarity