Daily Archives: January 10, 2022

Orexin-A regulates dopamine D2 receptor in the mesolimbic circuit

AoS. Orexin-A regulates dopamine D2 receptor in the mesolimbic circuit

Orexin-A (orx-A) is a neuropeptide expressed exclusively in hypothalamic neurons. Orx-A acts through the activation of type-1 (Orx1R) and -2 (Orx2R) receptors present in the mesolimbic circuit and in other brain areas. These neuropeptides have been implicated