Tag Archives: AAV

Dramatically distinct tropism and transduction efficiencies of AAV serotypes following subconjunctival injection

Instead of relying on traditional drug modalities, gene therapies rely on delivery of  nucleic acids into patient’s cells to prevent, slow, stop or treat diseases. In the past decades, gene therapy has been broadly studied in pre-clinical

The role of monocytes in ANCA-associated vasculitides

The anti – neutrophil cytoplasm antibody (ANCA) – associated vasculitides (AAV) include granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), and eosinophilic granulomatosis with polyangiitis (EGPA). These rare systemic autoimmune diseases affect small and medium – sized blood vessels, and are characterized by necrotizing vasculitis,