Tag Archives: AEP

Tail regeneration in lizard is driven by key genes of the Wnt-pathway

The importance of lizards as models to analyze the process of organ regeneration is relevant since, differently from the classical amphibian models, these vertebrates are amniotes adapted to the terrestrial environment, therefore closer to mammals and humans.

Key genes for amniote organ regeneration detected in lizard transcriptomes shed new hope for limb regeneration in humans

While in water-adapted vertebrates (anamniotes: fish and amphibians) organ regeneration is relevant or outstanding, including in fins or limbs, in fully terrestrial vertebrates (amniotes: reptiles, birds and mammals) regeneration is absent or rare. Aside numerous anatomical and