Tag Archives: allergy

The allergies go marching on: the atopic march and the temporal relationship of allergic diseases

Atopic/allergic family of diseases affects >20% of the global population and encompasses allergic asthma, hay fever, food allergy, atopic dermatitis, and allergic rhinitis. Frequently, individuals with an allergic condition develop another allergic disease. The atopic march theory

Antigen-expressing regulatory T cells can protect against allergic reactions

AoS. Antigen-expressing regulatory T cells can protect against allergic reactions

Our immune systems are designed to protect us from dangerous foreign invaders, like viruses, bacteria or parasites. However, sometimes we respond to usually harmless foreign materials, e.g. pollens or food, the results of which can be mild

Interleukin-18: Critical molecule in promoting allergic diseases

First interleukin was discovered in 1977 from monocyte and termed as interleukin (IL)-1. Interleukins are the secreted proteins that bind to their specific receptors with leukocytes. They are recognized as a family of cytokines based on sequence

Chronic rhinosinusitis patients with gastroesophageal reflux disease have a significantly higher prevalence of atopy and asthma

An association between chronic rhinosinusitis ( CRS ) and gastroesophageal reflux disease ( GERD ) has been previously reported. GERD shares several similarities with the pathophysiology of CRS and atopy. CRS and GERD both can present with

Vitamin D may contribute to development of asthma

Asthma is a chronic inflammatory airway disease, which development mechanism has not been fully investigated yet. Despite the progress of medical science in asthma field, morbidity of this disease remains high worldwide. Scientists raise hypothesis that vitamin

Medicines – allergic reactions to antiepileptic drugs

Around 1% of the global human population – ca. 65 million – suffer from epilepsy – a chronic neurological disease with one of the most prominent symptoms being so called epileptic seizures. With a range of antiepileptic

The inflamed skin in atopic eczema contributes to the disrupted skin-barrier

Atopic dermatitis, also known as atopic eczema or neurodermitis, is a chronic allergic skin disease affecting 15 – 30 % of children and 2 – 10 % of adults in industrialized countries. Patients suffer from inflamed, red

Bad news for people with a penicillin allergy

There are over 500,000 hospitalizations annually in the U.S. in which patients will have a reported allergy against first line antibiotics. Beta-lactams are the largest group of antibiotics which include penicillins, cephalosporins, and carbapenems. These antibiotics are

Zinc supplementation and allergy

Zinc is an essential trace element and an important factor of approximately 300 human enzymes.  It plays an important role in cellular growth, differentiation, and apoptosis. The immune system with its fast growing rates is especially dependent

Allergic mechanisms of Eosinophilic oesophagitis

The concept of eosinophilic oesophagitis (EoE) as a food allergy seems foreign to many patients, and even physicians, since EoE does not exhibit the typical symptoms associated with allergic reactions such as hives, swelling, pruritus, wheezing or

Allergy: the latest technology in vitro in the service of an appropriate diagnosis

The countless and various allergen sources from both the plant kingdom is to the animal kingdom constantly stimulate our immune system.So the allergy diagnostics laboratory is evolving using new technologies such as molecular biology, nanotechnology to highlight