Tag Archives: anesthesia

Duloxetine: a promising perioperative analgesic

Atlas of Science. Duloxetine: A Promising Perioperative Analgesic.

Duloxetine is a dual serotonin-norepinephrine receptor inhibitor that is commonly used as an antidepressant. This drug has traditionally been used for chronic pain conditions, such as fibromyalgia and back pain, showing positive recovery outcomes. Given these analgesic

Cellular stress and AMPK activators including metformin and the anesthetic drug propofol promote restoration of human consciousness

Cellular stress and AMPK activators including Metformin

The neural mechanisms that give rise to human consciousness have been described as one of the greatest and most profound mysteries in all of modern medicine. The use of general anesthetics to induce loss of consciousness (LOC)

Molecular mechanisms of gastrointestinal disorders caused by general anesthesia

Nowadays it is impossible to imagine surgery procedures without general anesthesia. From the wide variety of general anaesthetics both intravenous (such as propofol, ketamine, fentanyl etc.) and inhalation anesthetics (such as isoflurane, sevoflurane, desflurane etc.) are some

Levosimendan to reduce mortality in cardiac surgery (CHEETAH trial)

Over the past decade, there was a significant decline of mortality after cardiac-surgery. Although the average perioperative mortality for elective procedures currently is 1% to 2%, the rate of major complications remains high. Low-cardiac-output syndrome (LCOS, a

Comparison of anesthetic vaporizers

In many research laboratories that use small animals, anesthesia is used for a variety of procedures. The most common and widely used anesthetic gas is isoflurane because it can be easily adjusted to control how “deep” under

Gas Man computer simulation mimics anesthesia care

Gas Man® computer simulation mimics anesthesia care and allows anesthesia care providers to improve patient safety. Major surgery requires an anesthesia professional to give general anesthesia to a patient. This often begins with a drug injected in

What is the right blood transfusion trigger?

Blood transfusions are used in medical practice every day all over the world. Their use is largely aimed at restoration of the necessary number of red blood cells (erythrocytes), which main goal is to transport the oxygen