Tag Archives: antibiotic resistance
Carbapenem-resistant Enterobacteriaceae: fighting mutants
Antibiotic resistance occurs when bacteria causing an infection survive after being exposed to a drug that, under normal conditions, would kill it or inhibit its growth. As a result, this surviving strains multiply and spread due to
Antibiotic tolerance in bacteria: how to regain susceptibility?
Bacteria use a plethora of mechanisms to evade killing by antibiotics. Resistance is the best documented mechanism. Here, genetic changes in the bacterial DNA result in antibiotic insensitivity. As a consequence, resistant bacteria are able to grow
The difference of an amide to ester in polymers does the magic
Antibiotics kill bacteria by a specific targeting mechanism, and thereby, bacteria quickly develop resistance to antibiotics. The bacterial cell membrane is pivotal to its survival and is considered its Achille’s heel. Killing bacteria by attacking their cell
The nature of bel-1 attC stabilizes its genetic environment and contributes to antibiotic resistance spreading
The rapid emergence of antibiotic resistance is a worldwide crisis, endangering the efficacy of antibiotic treatment. Multidrug resistance in Gram negatives is now recognized as an issue of worldwide interest. Those bacteria possess various resistance mechanisms compromising
The silent go-between – the role of the microbiota as intermediator in horizontal gene transfer
Horizontal gene transfer (HGT) (also known as lateral gene transfer) is a powerful genetic process, in which DNA is transmitted from a donor organism to a recipient organism that is not its offspring. Thus, acquisition of DNA
Rapid detection of polymyxin-resistant Enterobacteriaceae from blood cultures
Enterobacterial strains resistant to extended-spectrum cephalosporins, carbapenems, aminoglycosides, fluoroquinolones are increasingly reported increasingly reported worldwide. Those strains remain mostly susceptible to polymyxins such as colistin. Polymyxins that are old antibiotics have been used until recently mostly in
Can bacteria resist a new antibacterial method?
Antibiotic resistance in bacteria is on the rise worldwide, making some previously-treatable infections incurable or even life-threatening. Thus there is a growing need for the discovery and development of new antibacterial methods of disinfection. Ideally these methods
