Tag Archives: antibiotic resistance

Antibiotic tolerance in bacteria: how to regain susceptibility?

AoS. Antibiotic tolerance in bacteria.

Bacteria use a plethora of mechanisms to evade killing by antibiotics. Resistance is the best documented mechanism. Here, genetic changes in the bacterial DNA result in antibiotic insensitivity. As a consequence, resistant bacteria are able to grow

The difference of an amide to ester in polymers does the magic

The difference of an amide to ester in polymers does the magic. AoS

Antibiotics kill bacteria by a specific targeting mechanism, and thereby, bacteria quickly develop resistance to antibiotics. The bacterial cell membrane is pivotal to its survival and is considered its Achille’s heel. Killing bacteria by attacking their cell

The nature of bel-1 attC stabilizes its genetic environment and contributes to antibiotic resistance spreading

Schematic representation of integrons containing the blaBEL-1 gene

The rapid emergence of antibiotic resistance is a worldwide crisis, endangering the efficacy of antibiotic treatment. Multidrug resistance in Gram negatives is now recognized as an issue of worldwide interest. Those bacteria possess various resistance mechanisms compromising

The silent go-between – the role of the microbiota as intermediator in horizontal gene transfer

Horizontal gene transfer (HGT) (also known as lateral gene transfer) is a powerful genetic process, in which DNA is transmitted from a donor organism to a recipient organism that is not its offspring. Thus, acquisition of DNA

Rapid detection of polymyxin-resistant Enterobacteriaceae from blood cultures

Enterobacterial strains resistant to extended-spectrum cephalosporins, carbapenems, aminoglycosides, fluoroquinolones are increasingly reported increasingly reported worldwide. Those strains remain mostly susceptible to polymyxins such as colistin. Polymyxins  that are old antibiotics have been used until recently mostly in

Can bacteria resist a new antibacterial method?

Antibiotic resistance in bacteria is on the rise worldwide, making some previously-treatable infections incurable or even life-threatening. Thus there is a growing need for the discovery and development of new antibacterial methods of disinfection. Ideally these methods