Tag Archives: carcinoma
Expression of mTOR-signalling pathway proteins in skin squamous-cell carcinomas before and after conversion to mTOR-inhibitors
Inhibitors of the Mammalian Target of Rapamycin (mTORis) are drugs exerting both immunosuppressive and antitumor effects, and are thereby used in organ-transplant recipients (OTR) in order to both prevent allograft rejection and to reduce the risk of
Immunological changes associated with hepatocellular carcinoma development
The body’s immune defense mechanisms play an important role in the inhibition or progression of liver diseases. We assessed the expression levels of different immune cells and cytokines in patients with chronic hepatitis C (CHC), liver cirrhosis
Oncogenic role of CircPVT1 in head and neck squamous cell carcinoma
Circular RNAs (circRNAs) are a class of endogenous non-coding RNAs that have recently shown to behave as gene regulators in eukaryotic cells, extending our previous knowledge regarding the diversity and complexity of the transcriptome. Nowadays, circRNAs have
Erufosine increases RhoB expression in oral squamous carcinoma cells independent of its anticancer mechanism of action
Erufosine is an ether–lipid-derived synthetic compound belonging to the group of alkylphosphocholines (APCs). This chemotherapeutic agent exhibits pronounced anti-leukemic activity without affecting the normal hematopoiesis and exerts its influence by modulating signal transduction pathways in malignant tumor
