Tag Archives: cell migration

Expression, purification and functionality of bioactive recombinant human vascular endothelial growth factor VEGF165 in E. coli

Angiogenesis, the growth of blood vessel from the existing vasculature, depends on the expression of various growth factors but Vascular Endothelial Growth factor (VEGF) ranks as the key inducer and the central mediator that promotes vascular permeability.

Rain, rain go away, little amoebas want to race

Soil living amoeba Dictyostelium discoideum has been used as a leading model organism for studying eukaryotic cell differentiation and directional cell migration. These functions are interconnected: starved Dictyostelium cells form multicellular aggregates by directional cell migration, and

New coordination between F-actin and microtubules

Cells maintain vesicles transportation, cell migration, cell polarity, mitosis, cell shape and even cell signaling through cytoskeleton, which is the most conservative and essential structures in diverse organism. F-actin and microtubule, two components of the cytoskeleton, have

CITED1 is a potential therapeutic target for metastatic melanoma

Cancer kills over 8 million people every year. What makes it so deadly is its ability to spread from the organ where it originates to the rest of the body, a process known as metastasis. Even though

Studying the interactions that trap cells in circulation

Healthy blood stem cells and invasive tumor cells use similar mechanisms to exit the circulatory system and penetrate other tissues. Cell migration is a multi-step process in which a number of adhesion molecules find their partners and

Gene expression changes underlying prostate cancer metastasis

Prostate cancer is one of the most common cancers among men. The American Cancer Society estimates that there will be 220,800 new cases of prostate cancer in 2015 and 27,540 prostate cancer related deaths. The National Cancer