Tag Archives: channels

Optimal level of membrane cholesterol guarantees the proper functioning of Kv channels

depletion or enrichment of plasma membrane cholesterol

Cholesterol is the most abundant lipid of the mammalian plasma membrane. It is well known that cholesterol influences membrane biophysical properties and regulates the activity of multiple types of ion channels, including K+ channels. The reported mechanisms

A simple method for the Study of Acid Sensing Ion Channels (ASICs) by fluorescence

The presence of severe acidosis has been demonstrated to be associated to several pathological conditions, such as multiple sclerosis, brain trauma, spinal cord injury and epilepsy as well as in inflammatory pain, to cite the most relevant.