Tag Archives: connexin

Gap junction assembly mechanisms in the cochlea

Gap junction assembly mechanisms in the cochlea. AoS

Hearing loss is the most common congenital sensory deficit. About 1-3 in 1000 children are affected at birth or during early childhood by severe hearing loss, which is defined as prelingual deafness, with at least half of

Cells must communicate to maintain normal uterine and placental functions

Cell-cell communication through specialized channels known as gap junctions (Fig. 1) regulate cellular metabolism and coordinate cellular functions during growth and differentiation of organs and tissues. Gap junctions are composed of six proteins known as connexins (Cx)

Functional behavior of neuronal networks interconnected through electrical synapses

Gap junction (GJ) channels, which allow direct transfer of electrical signal and exchange by metabolites between cells, are formed of 21 member of connexin (Cx) protein family in humans. Hundreds of GJ channels clustered in junctional plaques