Tag Archives: cytokine
Immunological changes associated with hepatocellular carcinoma development
The body’s immune defense mechanisms play an important role in the inhibition or progression of liver diseases. We assessed the expression levels of different immune cells and cytokines in patients with chronic hepatitis C (CHC), liver cirrhosis
Profiling biologics in circulating human whole blood
Functional and safety assessments of biologics prior to first-in-human (FIH) is key to understand the mode-of-action and safety profile. We have made use of an ex-vivo whole blood assay for its potential in assessment of antibody-based drug
How to build a communication system for cells
Single cell organisms, such as amoebae, are able to live independently without the need for extracellular communication systems. However, multicellular organisms, such as insects, fish and mammals, require systems that permit individual cells to communicate to one
Allelic variations within genes coding for cytokines among Orang Asli in Peninsular Malaysia: New candidate genes for future disease studies
Cytokines are a set of low molecular weight proteins/glycoproteins secreted by almost all types of cells. They regulate cell growth, immune response and blood cell development in the bone marrow. Genetic variations in cytokine genes include single
