Tag Archives: drug
Adding phospholipid to drug formulation: a promising approach to improve drug absorption
For a patient to benefit from the therapeutic effects of any medicine, the prerequisite is that the drug is adequately absorbed after drug intake. Unfortunately, at least 40% of the marketed drugs and up to 90% of
New drugs for cancer treatment
Cancer is a major cause of death and more than 1 million people in the United States are diagnosed with cancer each year. Finding more effective methods to treat cancer remains a challenge, and researchers are working
Allergic reaction to drug used to treat pulmonary hypertension
Treprostinil belongs to a category of drugs called prostacyclins, used to treat high blood pressure in the lungs, otherwise known as pulmonary arterial hypertension. It is available in an intravenous, subcutaneous, inhaled and oral form. The most
Unlocking trafficking impasse in life-and-death struggle of leukemic cells
Lymphocytes are immune system cells devoted to the defence against enemies coming from both outside (i.e. bacteria and viruses) and inside (tumours). Several times per day these cells escape from the blood and enter into the immune
Tests for biochemical detection of carbapenemase-producing Enterobacteriaceae
Multidrug resistance (MDR) to antibiotic in bacteria is becoming now a major issue worldwide. Its development worldwide may comprise the efficacy of the modern medicine such as transplantation, heavy surgery or hospitalization in intensive care units. Therefore,
Smart tumor suppression via intracellularly delivered drug
With the rapid metabolism of tumor cells, the microenvironments of tumor tissue and cells present acidity, while the pH maintains at about 7.4 in normal extracellular matrices and blood. In detail, the extracellular pH in tumor tissue
Liver Models for the Development of New Antiviral Drugs
The emergence of novel viruses such as the MERS coronavirus and new variants of well-known viruses such as avian influenza viruses still constitutes a major medical problem and demonstrates the necessity to develop new antiviral drugs. Normally,
