Tag Archives: glycosylation

TMEM165; The Bermuda triangle of glycosylation and Golgi Mn homeostasis

During evolution, eukaryotic cells have acquired a complex network of endomembranes delimiting distinct organelles with specific cellular functions. In mammals, the rough endoplasmic reticulum (ER) and the Golgi apparatus are two key organelles of the secretory pathway

The autonomous glycosylation of Giant, but sweet, viruses

The most of proteins carry sugars on them, which significantly modify their properties such as biological activity, solubility and resistance to protein-degrading enzymes. The sugars on proteins drive several fundamental biological mechanisms, such as hormones response, immune