Tag Archives: homeostasis

The protein TMEM147 is a novel regulator of cholesterol homeostasis in human cells

In terrestrial vertebrate animals, cholesterol is a major sterol lipid with multiple, critically important biological roles. In cells, it is a key constituent lipid of the plasma membrane, affecting its fluidity and stiffness and acting as an

The voltage-gated potassium channel, Kv1.3, at the crossroads of glial functions in glioma

The voltage-gated potassium channel, Kv1.3, at the crossroads of glial functions in glioma

Glioblastoma multiforme (GBM) is one of the most lethal cancers in adult humans, with a frequency of 6:100.000 people. Despite the current three-modality therapy, which includes surgery, radiation and chemotherapy, the clinical outcome of GBM patients remains

Disengaging ATF6 from DREAM for neuroprotection

Disengaging ATF6 from dream for neuroprotection

To study early changes in neuronal function during the pre-symptomatic phase of a given neurodegenerative disease is very important. It could deliver early diagnostic markers, offer prognostic clues about disease progression and uncover novel therapeutic targets for

Incretin hormones and brain microglia team up to regulate brain homeostasis

The entire human body is made up of many complicated cells, processes, and interactions. As scientific discoveries are made, it becomes increasingly more evident how multidimensional and interconnected all of the biological systems and pathways of the

Sugar induces sleep by activating the neurons responsible for sleep onset

Contrary to what one might think, sugar promotes sleepiness and not hyperactivity. There may be a good reason to sleep after a high-sugar meal. That is the conclusion of a new study published by neuroscientists at ESPCI