Tag Archives: hypoxia

How mitochondria “sense” and respond to changes in oxygen concentration in vivo

AoS. How mitochondria sense

Mitochondria – intracellular organelles – are our organism’s “powerhouse”, the main oxygen sensors that play the signaling role as modulators of oxygen consumption and regulators of the rate of oxygen delivery from the extracellular environment. Changes in

Look ma, no air

link between aerobic respiration and anaerobic respiration

Until recently, it has been conventional thinking that mammals cannot live without oxygen. This has been challenged by studies demonstrating survival of mole rats without oxygen for extended periods of time. The ability of mammalian cells to

Hypoxia mimetic blocks adipocyte differentiation but induces lipid accumulation

Obesity is one of the most immediate health threats in industrialized countries, increasing morbidity and mortality.  It is characterized by an excessive increase of white adipose tissue. Adipose tissue is a tissue with high plasticity, having the

Effects of hypoxia/reoxygenation in the antioxidant system of crabs

Variations in the concentration of dissolved oxygen in water naturally induce hypoxia/reoxygenation cycles in various regions of aquatic environments of freshwater (rivers and lakes) and marine (coastal areas). However, in recent decades, human activities that discharge domestic

Impacts of life at 2300 m

Populations all over the world live high up in the mountains. The main mountain ranges with long term settlements include the Himalayas in Asia, the Andes in South America and the Ethiopian highlands in Africa. Researchers could

Oxygen affects buds burst in grapevine

Grapevine is the most economically important fruit crop worldwide and is the mainstay of rural communities in over 100 countries. However, grapevine production is concentrated in latitudes of 30°-50°, and largely in maritime regions, due to its