Tag Archives: inflammation
Updates on the pathophysiology of systemic sclerosis
Systemic sclerosis (SSc) is a heterogeneous connective tissue disease with autoimmune component, inflammation, and progressive fibrosis of conjunctive tissues of the skin and internal organs. Lung involvements are a major cause of concern as pulmonary fibrosis and
Recharged autologous stem cells to combat cartilage defects in osteoarthritic patients
Inflammation is one of the greatest challenges for physicians and researchers working to find new strategies to regenerate patients’ damaged and deteriorated cartilage. Although humans have stem cells which can aid in many tissue repair processes throughout
Obesity protects inflamed dialysis patients
A high body mass index (BMI) is linked to longer survival terms for several serious chronic debilitating diseases. A large European epidemiological study shows that this protective effect does not apply to all patients with a high
Nonsteroidal anti-inflammatory drugs attenuate lung carcinogenesis in smoking female mice
Chronic inflammation plays a crucial role in the development of cancer in general and of cigarette smoke (CS) – related lung cancer in particular. Accordingly, anti-inflammatory drugs, among which the extensively used nonsteroidal anti – inflammatory drugs
A small RNA, microRNA-155, “micromanages” inflammation and renewal of neurons in the brain
The immune system is like a silent army, protecting the body from enemy viruses and bacteria. Inflammation is part of this response, acting to eliminate pathogens and initiate tissue repair. Most of the time, our immune systems
Highlighting inflammatory markers in anxiety disorders
Anxiety disorders, often originating early in life, are very common and effect 28.3% of the population. With this high prevalence comes an associated cost to the economy, mostly related to the extensive overuse of primary care services
Cancer connection: study of inflammation offers tantalizing clues
The body displays a remarkable capacity for healing wounds— a process we often take for granted. Within a day, a finger we’ve carelessly nicked returns to normal. Behind the scenes, a crucial mediator of the body’s inflammatory
NEIL2 repairs DNA damage within active genes, maintains chromosome end integrity, prevents inflammation
Mammalian cells are subjected to a plethora of exogenous and endogenous agents that cause damage to the cellular DNA. One of the major sources of such damage is oxygen-derived molecules and free radicals, collectively termed “Reactive Oxygen
An internal granuloma investigated by light and scanning electron microscopy
Caries and Periodontitis are not the only reasons why patients may suffer from problems with their teeth. There are far less frequent occuring phenomena causing dental treatment need, which however are of research interest in respect to
Topical administration of an antimicrobial peptide as a new strategy for improved burn wound healing
Burn wounds represent a major global concern, as more than 100 million people worldwide are estimated to experience burn injuries every year. These may be caused upon exposure to heat, radiation, chemicals or electric shocks, often resulting
Obesity causes lung dysfunction and breathing troubles by increased cysteinyl leukotrienes pathway
Increased body weight is a chronic health problem which has emanated from the globalized food market and dietary habit. This has led to the different types of ailments which occur in obese individual simultaneously and referred to
Resveratrol is a potential remedy for the treatment of pancreatic fibrosis
The pancreas serves as both endocrine and exocrine glands in a human body in order to help food digestion and blood glucose regulation. In fact, more than 90% of the pancreatic mass comprises the exocrine cells which
Health benefits of haskap: Possible control of inflammation-mediated chronic disorders
Biologically active phytochemicals present in cool climate berries such as haskap (Lonicera caerulea L.) offer a great alternative therapy for mitigation of most of the chronic disorders. In general, polyphenols in fruits have shown the potential to
Omega-3 fatty acids ameliorate age-related hearing loss
We have evaluated the effects of a diet rich in omega-3 fatty acids on age-related hearing loss using a mouse model. These mice present early hearing loss, the symptoms appearing normally at 4 to 6 months of
Researchers describe “imm-unifying theory” capable of explaining multiple medical problems
About a year ago, investigators at the Shock Trauma Center in Baltimore, MD found that patients who had organ transplants fared quite well after traumatic events. The authors of the manuscript, which was published in the Journal
