Tag Archives: lysosomes

The lysosomal enzyme cathepsin D as novel therapeutic target for non-alcoholic steatohepatitis

The decrease in physical activity combined with increased caloric intake has led us to a global obesity epidemic. Obese patients can develop metabolic syndrome (MetS), which is a term used to assess the risk of a patient

Zooming in on the ‘big eaters’ in atherosclerosis: a key role for oxidation and cellular localization of fat

Our sedentary lifestyle combined with the enrichment of fat in our diet has led to an increase of diseases affecting the health of our cardiovascular system. Cardiovascular disease is one of the leading causes of death, with

Calcium disturbances in Parkinson’s disease

Parkinson’s disease is a common disorder of the brain that affects around 127,000 people in the UK alone. The disease is characterised by the loss of nerve cells (neurons) that control mobility. Symptoms include muscle stiffness, tremor