Tag Archives: pediatric cancer
LMO1 regulates a novel oncogenic pathway druggable for neuroblastoma
Neuroblastoma (NB) is derived from neural crest cells and its main developing sites are adrenal gland and sympathetic ganglions. It is the most common extracranial solid tumor in childhood, accounting for more than 7% of malignancies in
Surprisingly diverse impacts of SMARCB1 loss on gene expression programs in a lethal pediatric cancer
Malignant rhabdoid tumors (MRTs) are aggressive childhood cancers that are often resistant to chemotherapies and spread to other areas in the body (metastasis), making them one of the most lethal solid cancers known. Primary MRTs are frequently
