Tag Archives: phagocytosis

Cells with an appetite: munching at a single-cell level

Cells with an appetite: munching at a single-cell level

Phagocytosis is defined as the receptor-mediated uptake of large particulate matter. This process is particularly efficient in specialized immune cells such as macrophages, neutrophils and dendritic cells. These cells constitute the first line of defense against invading

Erythrocytes, not leukocytes, clear bacteria from blood circulation

After discovery of phagocytosis by Elie Metchnikoff in 1882, it has become an axiom that in human body white blood cells (leukocytes) are the main cells that engulf and destroy bacteria and other pathogens. But until recently, there has

Collateral damages and self-inflicted scars by inflammation in cardiovascular diseases

Inflammation is a double-edged sword used by the body to initiate the healing process. However, persistence of immune responses can cause progressive destruction of tissues culminating in self-destructive autoimmune reactions which is a hallmark of many diseases.