Tag Archives: ROS
NEIL2 repairs DNA damage within active genes, maintains chromosome end integrity, prevents inflammation
Mammalian cells are subjected to a plethora of exogenous and endogenous agents that cause damage to the cellular DNA. One of the major sources of such damage is oxygen-derived molecules and free radicals, collectively termed “Reactive Oxygen
The p53 gene is a human tumor suppressor which is involved in cell cycle regulation. It has an efficient ability to inhibit cell proliferation, by both blocking cell cycle progression and promoting apoptotic cell death in order
Photosensitization is a process in which a chemical compound (photosensitizer) that absorbs energy from light is able to transfer that energy to oxygen molecules. As a consequence, reactive oxygen species (ROS), highly toxic to living cells, are
The repetitive and continuous circle of resistance to anti-cancer agents was a primary focus of the above-titled articles recently published in Pharmacological Research. Gaining a basic understanding of why so many (possibly all) drugs currently available against
Imagine a world where one size does not fit all, wait that’s the world we live in now. So why is the treatment you get under the “one size fits all” umbrella, we are all different, right?