Tag Archives: Trypanosoma cruzi
Proline analogues present anti-Trypanosoma cruzi activity through inhibition of proline transporter
Trypanosoma cruzi is the protozoan parasite that causes Chagas disease, an illness that affects approximately 7 million people in Latin America. Nowadays there are only two drugs approved for Chagas treatment, benznidazole and nifurtimox. Both drugs were
Chagas disease a neglected ills without treatment
Chagas disease (CD) is transmitted by the parasite Trypanosoma cruzi, and was discovered in 1909 by the Brazilian medical doctor named Carlos Chagas. Until today, CD remains a serious public health problem, with more than 7 million
Polyamine transport increases drug resistance in the parasite Trypanosoma cruzi
The parasite Trypanosoma cruzi is the causative agent of Chagas disease, an illness affecting millions of people in America. The only drugs approved against Chagas disease are nifurtimox and benznidazole, which were discovered almost half a century
The search for new drug candidates to treat Chagas disease
Chagas disease (CD) is a parasite-born pathology caused by a unicellular microorganism called Trypanosoma cruzi. This illness causes a significant morbidity and mortality in the developing world, being endemic in 21 countries across Latin America, representing also
Resveratrol: A natural product that kills the parasite responsible for Chagas disease
Chagas disease is a neglected illness affecting approximately 10 million people in the Americas, caused by a parasitic microorganism called Trypanosoma cruzi. There are only two drugs used against Chagas disease, which are effective only in the
