Tag Archives: valproic acid

The mood stabilizer valproic acid tunes up abnormal circadian rhythms in mania

Circadian clocks rule our lives. In the course of evolution, almost all living creatures developed molecular mechanisms that optimally prepare our bodies for predictable , recurring events related to the regular alternations between day and night. This

Use of valproic acid during postoperative chemoradiotherapy for glioblastoma may improve survival outcome

Glioblastoma (GBM) is the most common primary brain neoplasm. The standard therapy for GBM consists of surgical resection to the extent that is safely feasible, followed by chemoradiotherapy (CRT) with temozolomide. The prognosis is still poor; the

Valproic acid treatment for brain tumors

Tumors arising in the brain represent only 2% of all cancers diagnosed in the United States with 23,000 new cases and 14,000 deaths annually.  The World Health Organisation (WHO) classifies brain tumors from grade 1 to grade