Daily Archives: August 3, 2016

Direct regulation of G protein signal strength as a new drug target?

Heterotrimeric GTP-binding proteins (G proteins) remain an important but elusive target in drug discovery. G proteins adapt cell behavior in response to signals generated by cell surface receptors, G protein coupled receptors (GPCRs). Clinical interest in G

The benefits and safety of pulmonary rehabilitation in patients with lymphangioleiomyomatosis (LAM)

Lymphangioleiomyomatosis (LAM) is currently considered a low-grade neoplasm that mainly affects young women, and is characterized by the presence of diffuse pulmonary cysts. Several studies have shown that patients with LAM have reduced exercise capacity secondary to