Daily Archives: February 13, 2018

How does phenobarbital, a therapeutic sedative, activate a nuclear receptor through phosphorylation?

Steroid hormones activate a family of nuclear proteins called nuclear receptors to regulate every aspect of human physiology, reproduction, development, differentiation, metabolism and immunity. A nuclear receptor molecule is comprised of two major structural domains; DNA-binding (DBD)

mRNA decay activity in neurons regulates survival of worms at high temperatures

The ability of an organism to quickly alter or fine-tune its gene expression profile as a response to unfavorable and stressful conditions is a vital trait that can determine its chances of growth and survival in unstable