Daily Archives: December 10, 2018
Cholesterol manipulation switches the production of “toxic Aβ” to “protective Aβ”
The amyloid hypothesis maintains that the pathogenesis of Alzheimer’s disease (AD) is driven by the production and accumulation of amyloid-β (Aβ) peptides in the brain. Consequently, many therapeutic strategies to reduce Aβ production have been examined. However,
