Daily Archives: March 17, 2020
HIV-1 alters mitochondria in neurons and contributes to HIV-associated neurocognitive disorders
Human immunodeficiency virus type-1 (HIV) enters the brain during the initial stages of infection and can cause neurologic dysfunction. Despite the success of HIV treatment through combination antiretroviral therapy (ART), impaired neurocognitive function remains an important problem
Access to modified peptides with heterocycle backbones using combinatorial chemistry
Applications of peptides in medicinal chemistry have several inherent limitations which can be resolved by use of peptide-like molecules. The cleavage of amide bond by proteases, low permeability, rapid metabolic processing, excretion and unwanted side effects are
